Cells controlled in 3D!

HeLa cell division while confined at 3 µm

Applications of the cell confiner:


1. Study cell dynamics triggered by/under mechanical effects:

a. Migration
b. Cell division
c. Induce autophagy
d. Mechanotransduction
e. Mechanics of the nucleus
f. etc.

2. Do co-culture of cells

3. Use with special substrates – functionalized, micropatterned, etc.

4. Mimick the natural cell environment

5. Imaging – the confiner is convenient as a complementary tool in multiple and single cell imaging and it is even compatible with high-resolution.

Advantages: all the organelles of the cell are in the same plane of visualization; it decreases the optical aberrations caused by the spherical like shape of the cells.