4DCELL DEVICE

Micropillars

READ-OUTS

Durotaxis, haptotaxis, substrate stiffness control

STANDARD CULTURE LIMITATION

Cell migration plays a major role in many fundamental biological processes. As they anchor and pull on their surroundings, adhering cells actively probe the stiffness of their environment. However, it is difficult in a standard Petri dish to establish a stiffness gradient.

DUROTAXIS AND HAPTOTAXIS ASSAY BENEFITS

EXAMPLE

REFERENCE

[1] Rühe, J. et al. (2016). Langmuir, 32(46), 12190–12201.