MICROWELLS FOR ASSEMBLY OF SPHEROIDS PETRI DISHES
Explore the potential of microwells to form functional and reproducible spheroids
4Dcell offers petri dishes containing hydrogel-based microwell structures specially designed for the spontaneous formation of uniform spheroids. The anti-adhesive properties of the hydrogel facilitates rapid self-assembly of cell aggregates into compact spheroids.
The adhesive bottom surface of each microwell anchors the spheroids in place. This prevents the loss of spheroids during typical manipulations (medium exchange, drug addition, etc), and makes the location of each spheroid predictable. Has the hydrogel is optically transparent it is fully compatible with conventional microscopy.
> READY TO USE
Plate your cells directly on the microstructured substrates
> KEEP YOUR SPHEROIDS IN PLACE
The anchoring point helps keep the spheroids in each microwells during medium exchanges
> REPRODUCIBLE SIZE AND SHAPE
The size of the spheroids depends only on the cell seeding concentration
HOW TO HANDLE YOUR PETRI DISHES
FEATURES & BENEFITS
4DCELL GLASS BOTTOM PETRI DISHES WITH MICROWELLS FOR SPHEROIDS’ ASSEMBLY:
petri dishes with glass bottom ( #1.5, 0.16 – 0.19 mm), micro-well size 10 mm
The microstructured substrates are made of biocompatible polyethylene glycol gel
Optionally the microwells can be coated with an ECM matrix to increase the adherence of the spheroid to the attachment point
The gels are provided in a water based solution that keeps their mechanical and optical properties
SCHEMATICS OF THE PETRI DISHES :
(image of the macrowell with the cell seeding well and microwells)
DIMENSIONS OF THE MICROWELLS:
TOP VIEW OF THE MICROWELLS + CROSS SECTION
ADDITIONAL INFORMATION:
If this device does not meet your needs, get in touch with us! We can personalize it for you.
CANCER
> Cell shape standardization
ORGAN PHYSIOLOGY
> Migration of somatic and cancer cells
> Cell shape standardization
> Cardiomyocyte beating properties
> Neural network
> Detection of bile canaliculi in hepatocytes
> Tissue geometry mimicry
RARE DISEASES
> Cell nucleus integrity
> Nuclear plasticity
> Neural network
FUNDAMENTAL RESEARCH
> Cell shape standardization
> Standardized connectivity between neurons
BIOMOLECULAR IN VITRO MODELS
> Spatial autoorganization of macromolecules (at the microscale)
