> MICROCHANNELS DISH

Let’s guide your cells

Microchannels Dish

The PDMS microchannels are already bound to the 35 mm glass bottom petri dish.

Just rinse the microchannels, add some extracellular matrix protein and load your cells!

 

> Ready to use

All you need is a pipette to load your cells.

 

> Large range of sizes available

From 3 to 1000 µm width, adapted to single cell or collective migration.

 

> High quality live imaging

Glass bottom petri dish to reduce microscope working distance.

> MICROCHANNEL’S DIMENSIONS

 

The 3D shape and stress conditions imposed to your cells depend on the microchannels size. Each chip has 6 ranges of microchannels and 9 access ports.

Microchannels features
small microchannels cell migration

Small microchannels chip design available in different heights (MC001, MC002, MC003, MC004).

medium microchannels cell migration

Medium microchannels chip design (MC005)

> MICROCHANNELS WITH CONSTRICTIONS

constriction microchannels
constriction microchannels

Example of a 4Dcell microchannel with a constriction of 1.5 µm width.

> CANCER

 

Migration of metastatic cells

Nuclear plasicity in mestastasis

DNA DSB repair (mechanically induced)

Angiogenesis

Immuno-oncology

 

> IMMUNOLOGY

 

Cell-cell interaction

Migration of immune cells

Antigene searching

Extravasation/diapedesis

Chemotaxis/haptotaxis

 

> ORGAN PHYSIOLOGY

 

Migration of cancer cells

Shear stress

Angiogenesis

Epithelium permeability/brain blood barrier

Neural network

 

> RARE DISEASES

 

Cell nucleus integrity

Nuclear plasticity

Neural network

 

> FUNDAMENTAL RESEARCH

 

Cell adhesion

Example of iBMD Cells migrating within microchannels of different sizes (0.5 image/min)
Réf. video by 4Dcell partner Dr Pablo Vargas, Curie Institute/UMR144