> GENERAL REVIEWS ABOUT [ADVANCED CELL CULTURE TECHNOLOGIES]

CELL CONFINEMENT

3D Cell Culture & Cell Confinement

The problems of dissimilarity between 2D cell culture and a cell’s natural environment have become evident after numerous studies demonstrated that the cellular microenvironment  … read more

Cell Confiner - Pack microscope

MICROPATTERNING

Revolutionizing cell culture by implementing adhesive micropatterns to control the microenvironment

The problems of dissimilarity between 2D cell culture and a cell’s natural environment have become evident after numerous studies demonstrated that the cellular microenvironment  … read more

4Dcell micropatterning quartz

MICROCHANNELS

Discovering 3D cell culture through a modern microfluidic device, the microchannels

Cells in the body are physically confined by neighboring cells, tissues, and the extracellular matrix. Then, the microenvironment surrounding a cell significantly influences … read more

Microchannels on chip on petri dish 4DCell

MAKE YOUR NEURONS HAPPIER!

Control, guide and evaluate outgrowth of neuronal culture

Neurons are often cultured in vitro on a flat, open, and rigid substrate, a platform that does not reflect well the native microenvironment of the brain. The cell’s microenvironment is defined by … read more

Make your neurons happier

> ORGAN IN WELL – HEPATOTOXICITY

New technologies for the prediction of hepatotoxicity during preclinical studies 

Considered as the main reason to remove drugs from the market, drug induced liver injury (DILI) is a major concern of pharmaceuticals industries to decrease the hepatotoxicity of drugs… read more

HepaRG spheroid

> ORGAN IN WELL – CARDIOTOXICITY

New technologies for the prediction of cardiotoxicity during preclinical studies 

Drug safety is among the main concerns of pharmaceuticals who fight to improve it. In fact, both the long-term and the high costs of drug development lead to an urgent improvement… read more

Cardiomyocyte

> FIBROBLASTS

Discovery of their properties and emphasis on the assays used to test them

Fibroblasts are mesenchymal cells, which provide support and structure to the functional cells of the organs. They are major producers of collagen and other extracellular matrix (ECM) components, and are able to… read more

Phase contrast microscopy image of fibroblasts from a mouse embryo