Publications

using 4Dcell’s products

MICROPATTERNS 

A switchable light-responsive azopolymer conjugating protein micropatterns with topography for mechanobiological studies

Chiara Cimmino, Paolo A. Netti, and Maurizio Ventre

Front Bioeng Biotechnol. 2022;  Read the paper here

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MICROPATTERNS 

A role for nuclear stretching and NPCs changes in the cytoplasmic-nuclear trafficking of YAP: An experimental and numerical modelling approach

Stefania Saporito, Carlo F. Natale, Costantino Menna, Paolo Antonio Nettia, Maurizio Ventre

Materials Today Bio 2022;  Read the paper here

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MICROPATTERNS 

Monitoring the maturation of the sarcomere network: a super-resolution microscopy-based approach

Skorska A, Johann L, Chabanovska O, Vasudevan P, Kussauer S, Hillemanns M, Wolfien M, Jonitz-Heincke A, Wolkenhauer O, Bader R, Lang H, David R, Lemcke H

Cell Mol Life Sci 2022;  Read the paper here

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MICROPATTERNS 

ERRα coordinates actin and focal adhesion dynamics

Violaine Tribollet, Catherine Cerutti, Alain Géloën, Emmanuelle Danty-Berger, Richard De Mets, Martial Balland, Julien Courchet, Jean-Marc Vanacker, Christelle Forcet

Cancer Gene Therapy 2022;  Read the paper here

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MICROPATTERNS  

Lamin mutations cause increased YAP nuclear entry in muscle stem cells

Daniel J. Owens, Martina Fischer, Saline Jabre, Sophie Moog, Kamel Mamchaoui, Gillian Butler-Browne, Catherine Coirault

Cells 2020;  Read the paper here

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MICROPATTERNS  

Compliant substrates enhance macrophage cytokine release and NLRP3 inflammasome formation during their pro-inflammatory response

Joan-Carles Escolano, Anna V. Taubenberger, Shada Abuhattum, Christine Schweitzer, Aleeza Farrukh, Aránzazu Del Campo, Clare E. Bryant, Jochen Guck

Front. Cell Dev. Biol. 2021;  Read the paper here

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MICROPATTERNS  

Reprogramming progressive cells display low CAG promoter activity

Xiao Hu, Qiao Wu, Jian Zhang, Jonghun Kim, Xinyue Chen, Amaleah A. Hartman, Anna E. Eastman, In-Hyun Park, Shangqin Guo

Stem Cells 2021;  Read the paper here

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MICROCHANNELS

Slow integrin-dependent migration organizes networks of tissue-resident mast cells

Lukas Kaltenbach, Paloma Martzloff, Sarah K. Bambach, […], Marc Bajénoff, Dominic Grün & Tim Lämmermann

Nature Immunology 2023; Read the paper here 

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MICROCHANNELS

Nuclear segmentation facilitates neutrophil migration

Connie Shen, Eva Mulder, Wiebe Buitenwerf, Jérémy Postat, Aron Jansen, Matthijs Kox, Judith N. Mandl, Nienke Vrisekoop

J Cell Sci 2023; Read the paper here 

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MICROCHANNELS

Specification of CNS macrophage subsets occurs postnatally in defined niches

Takahiro Masuda, Lukas Amann, Gianni Monaco, Roman Sankowski, […], Tim Lämmermann, Josef Priller, Katrin Kierdorf & Marco Prinz

Nature 2022; Read the paper here 

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MICROCHANNELS

Reprogrammed Schwann Cells Organize into Dynamic Tracks that Promote Pancreatic Cancer Invasion

Deborde S, Gusain L, Powers A, Marcadis A, Yu Y, Chen CH, Frants A, Kao E, Tang L, Vakiani E, Calo A, Omelchenko T, Jessen KR, Reva B, Wong RJ

Cancer Discovery 2022; Read the paper here 

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MICROCHANNELS

Snail augments nuclear deformability to promote lymph node metastasis of head and neck squamous cell carcinoma

Yin-Quan ChenChen-Yu HungMing-Tzo WeiJean-Cheng KuoMuh-Hwa YangHan-Ying ChengArthur Chiou

Front Cell Dev Biol 2022; Read the paper here 

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MICROCHANNELS WITH CONSTRICTIONS 

Formin-like 1 mediates effector T cell trafficking to inflammatory sites to enable T cell-mediated autoimmunity

Scott B. Thompson, Adam M. Sandor, Victor Lui, Jeffrey W. Chung, Monique M. Waldman, Robert A. Long, Miriam L. Estin, Jennifer L. Matsuda, Rachel S. Friedman, Jordan Jacobelli

eLife 2020; Read the paper here 

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MICROCHANNELS WITH CONSTRICTIONS   

Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton

Katharina Vestre, Irene Persiconi, Marita Borg Distefano, Nadia Mensali, Noemi Antonella Guadagno, Marine Bretou, Sébastien Wälchli, Catharina Arnold-Schrauf, Oddmund Bakke, Marc Dalod, Ana-Maria Lennon-Dumenil, Cinzia Progida

J Cell Sci. 2021; Read the paper here

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MICROSTRUCTURED HYDROGELS  

Adherens junction engagement regulates functional patterning of the cardiac pacemaker cell lineage

Kandace Thomas, Trevor Henley, Simone Rossi, M. Joseph Costello, William Polacheck, Boyce E. Griffith, Michael Bressan

Dev. Cell 2021;  Read the paper here

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CONTRACTILITY ASSAY  

A versatile high-throughput assay based on 3D ring-shaped cardiac tissues generated from human induced pluripotent stem cell derived cardiomyocytes

Magali Seguret, Patricia Davidson, Stijn Robben, Charlène Jouve, Céline Pereira, Cyril Cerveau, Maël Le Berre, Rita S. Rodrigues Ribeiro, Jean-Sébastien Hulot

eLife 2022;  Read the paper here

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CELL CONFINER  

Nuclear tension controls mitotic entry by regulating cyclin B1 nuclear translocation

Margarida Dantas, Andreia Oliveira, Paulo Aguiar, Helder Maiato, and Jorge G. Ferreira

J Cell Biol 2022;  Read the paper here

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CELL CONFINER  

The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior

Valeria Venturini, Fabio Pezzano, Frederic Català Castro, Hanna-Maria Häkkinen, Senda Jiménez-Delgado, Mariona Colomer-Rosell, Monica Marro, Queralt Tolosa-Ramon, Sonia Paz-López, Miguel A. Valverde, Julian Weghuber, Pablo Loza-Alvarez, Michael Krieg, Stefan Wieser, Verena Ruprecht

Science 2020;  Read the paper here

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CELL CONFINER  

A flagellate-to-amoeboid switch in the closest living relatives of animals

Thibaut Brunet, Marvin Albert, William Roman, Maxwell C. Coyle, Danielle C. Spitzer, Nicole King

eLife 2021;  Read the paper here

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CELL CONFINER  

Mechanisms of A-type lamin targeting to nuclear ruptures are disrupted in LMNA- and BANF1-associated progerias

Rhiannon M. Sears and Kyle J. Roux

Cells 2022;  Read the paper here

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CELL CONFINER  

Nuclear tension controls mitotic entry by regulating cyclin B1 nuclear translocation

Margarida Dantas, Andreia Oliveira, Paulo Aguiar, Helder Maiato, Jorge G. Ferreira

JCB 2022;  Read the paper here

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