Human 3D in vitro models
for drug discovery and preclinical testing
Organ-in-a-well® Platform.
4Dcell develops human in vitro models and experimental platforms to investigate how drug candidates affect cell and tissue function.
SmartHeart® Platform
Drug efficacy and cardiotoxicity
SmartHeart® is a 96-well platform for generating ring-shaped human 3D cardiac microtissues from iPSC-derived cardiomyocytes and cardiac fibroblasts.
It enables researchers to investigate compound effects on contractility, electrical activity and calcium dynamics.
PLATE YOUR CELLS. LET THEM BEAT. MEASURE.
Key technologies
3D, 2.5D & 2D in vitro SmartTechnologies
Self assembly of cell aggregates with a ring shape that facilitate contractility force measurements
Homogenous confinement of cells between two parallel planes to a defined micrometer height with sub micrometer resolution.
WHY 4DCELL?
SIMPLE USE TO MANAGE COMPLEXITY
4Dcell was born from a shared vision: providing biologists with cutting-edge biophysical solutions to develop alternatives to animal testing.
Our team of engineers and biologists came together to explore how material sciences and physics could revolutionize cell culture.
By designing innovative scaffolds, we create advanced 2D and 3D structures that guide cell organization, enabling the development of physiologically relevant in vitro models.
From the very beginning, we have been driven by two key principles: ease of use for scientists and strict reproducibility.
Our technologies are designed so that researchers can simply plate their cells without additional complexity, ensuring seamless integration into their workflows. At the same time, every 4Dcell product is developed with a strong focus on reproducibility, ensuring that each experiment yields consistent and reliable results.
By combining innovation, simplicity, and precision, 4Dcell empowers scientists to push the boundaries of in vitro research, accelerating discoveries while reducing reliance on animal models, offering more predictive, ethical, and scalable solutions for drug discovery, toxicology, and fundamental research.
COMMITTED TO NAMs AND THE FUTURE OF DRUG TESTING
4Dcell was one of the first european TechBio companies to pioneer the development of NAMs (New Approach Methodologies). We are proud to contribute to the global transition toward NAMs, which promote ethical, efficient, and human-relevant alternatives to animal testing.
Our advanced in vitro platforms, combining bioengineered microenvironments with high-content readouts, support more predictive models for drug discovery and toxicology.
By enabling organoid formation, cell maturation, and functional analysis in physiologically relevant conditions, 4Dcell technologies are shaping the next generation of biomedical research.