
Organ-in-a-well® Platform
2D & 3D models to redefine in vitro standards to select the right molecules
NAMs to accelerate drug market entry.
SmartHeart® Platform
Efficacy and cardiotoxicity
Years of work have led 4Dcell's R&D team to deliver an unprecedented cardiac model. The SmartHeart design enables an easy-to-use in vitro heart model, requiring only a low number of cells. Each well contains 9 rings, ensuring precise data points while enabling high-resolution imaging.
PLATE YOUR CELLS. LET THEM BEAT. MEASURE.

Key technologies
3D, 2.5D & 2D in vitro SmartTechnologies
Self assembly of cell aggregates with a ring shape that facilitate contractility force measurements
Hydrogel based microwells to form functional and reproducible spheroids. An anchoring point precludes them from being lost during medium exchange.
Homogenous confinement of cells between two parallel planes to a defined micrometer height with sub micrometer resolution.

WHY 4DCELL?
SIMPLE USE TO MANAGE COMPLEXITY
4Dcell was born from a shared vision: providing biologists with cutting-edge biophysical solutions to develop alternatives to animal testing.
Our team of engineers and biologists came together to explore how material sciences and physics could revolutionize cell culture.
By designing innovative scaffolds, we create advanced 2D and 3D structures that guide cell organization, enabling the development of physiologically relevant in vitro models.
From the very beginning, we have been driven by two key principles: ease of use for scientists and strict reproducibility.
Our technologies are designed so that researchers can simply plate their cells without additional complexity, ensuring seamless integration into their workflows. At the same time, every 4Dcell product is developed with a strong focus on reproducibility, ensuring that each experiment yields consistent and reliable results.
By combining innovation, simplicity, and precision, 4Dcell empowers scientists to push the boundaries of in vitro research, accelerating discoveries while reducing reliance on animal models, offering more predictive, ethical, and scalable solutions for drug discovery, toxicology, and fundamental research.
COMMITTED TO NAMs AND THE FUTURE OF DRUG TESTING
4Dcell was one of the first european TechBio companies to pioneer the development of NAMs (New Approach Methodologies). We are proud to contribute to the global transition toward NAMs, which promote ethical, efficient, and human-relevant alternatives to animal testing.
Our advanced in vitro platforms, combining bioengineered microenvironments with high-content readouts, support more predictive models for drug discovery and toxicology.
By enabling organoid formation, cell maturation, and functional analysis in physiologically relevant conditions, 4Dcell technologies are shaping the next generation of biomedical research.