> COVERSLIPS COATED WITH GELS

Tune stiffness to replicate the in vivo environment

Cells are cultured on polyacrylamide gel allowing to the cells to be in a 3D environment.

Using the gel coated coverslips, cells can be directly cultured in a substrate that resembles their in vivo stiffness. Cells can be cultured in an easy and fast way, since the coverslips are ready to be used.

 

> A wide range of stiffness available

From very hard (200 kPa) to very soft (1 kPa)

 

> Ready to use

Plate your cells directly

 

> Optically transparent

 

The 4Dcell coverslips coated with gels are provided into classic petri dishes in sterile individual plastic bags in 24 mL coverslips.

 

Stiffness of the substrate can be chosen from very hard (200 kPa) to soft (1 kPa)

Ready to use and coated with fibronectin

Bio-functionalization with ECM proteins

Adaptable to any cell culture substrate (from Petri dishes to 96 well plates)

Compatible with high-resolution optical microscopy systems

> CANCER

  • Cell shape standardization

 

> ORGAN PHYSIOLOGY

  • Migration of somatic and cancer cells
  • Cell shape standardization
  • Cardiomyocyte beating properties
  • Neural network
  • Detection of bile canaliculi in hepatocytes
  • Tissue geometry mimicry

 

> RARE DISEASES

  • Cell nucleus integrity
  • Nuclear plasticity
  • Neural network

 

> FUNDAMENTAL RESEARCH

  • Cell shape standardization
  • Standardized connectivity between neurons

 

> BIOMOLECULAR IN VITRO MODELS

  • Spatial autoorganization of macromolecules
    (at the microscale)