MICROCHANNELS DISH

Let’s guide your cells

Microchannels Dish Cell migration Non adherent cell migration

The PDMS microchannels are already bound to the 35 mm glass bottom petri dish.

Just rinse the microchannels, add some extracellular matrix protein and load your cells!

 

> READY TO USE

All you need is a pipette to load your cells.

 

> LARGE RANGE OF SIZES AVAILABLE

From 3 to 1000 µm width, adapted to single cell or collective migration.

 

> HIGH QUALITY LIVE IMAGING

Glass bottom petri dish to reduce microscope working distance.

HOW TO HANDLE YOUR MICROCHANNELS DISH

Microchannels in a Petri dish

FEATURES & BENEFITS

The 3D shape and stress conditions imposed to your cells depend on the size of the microchannels.

Each chip is provided in a 35 mm glass bottom petri dish in an individual sterile plastic bag

The thickness of the glass is approx. 170 μm.

The chips are provided in sets of 20 or 50 units. 

 

 

4DCELL MICROCHANNEL CHIPS STANDARD CATALOG

 

Each microchannels chip has 6 ranges of microchannels and 9 access ports. 

Microchannels features
Small microchannels cell migration

Small microchannels chip design available in different heights (MC001, MC002, MC003, MC004).

Medium microchannels cell migration

Medium microchannels chip design (MC005)

MICROCHANNELS WITH CONSTRICTIONS

Microchannels with constrictions, cell deformation, nucleus mecanism
constriction microchannels
Microchannels with constrictions, cell deformation, nucleus mecanism

Example of a 4Dcell microchannel with a constriction of 1.5 µm width.

CANCER

 

> Migration of metastatic cells

> Nuclear plasticity in metastasis

> DNA DSB repair (mechanically induced)

> Angiogenesis

> Immuno-oncology

 

IMMUNOLOGY

 

> Cell-cell interaction

> Migration of immune cells

> Antigene searching

> Extravasation/diapedesis

> Chemotaxis/haptotaxis

 

ORGAN PHYSIOLOGY

 

> Migration of cancer cells

> Shear stress

> Angiogenesis

> Epithelium permeability/brain blood barrier

> Neural network

 

RARE DISEASES

 

> Cell nucleus integrity

> Nuclear plasticity

> Neural network

 

FUNDAMENTAL RESEARCH

 

> Cell adhesion

Example of iBMD Cells migrating within microchannels of different sizes (0.5 image/min)
Réf. video by 4Dcell partner Dr Pablo Vargas, Curie Institute/UMR144

OTHER PRODUCT RELATED TO MICROCHANNELS