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5000+ ORGANOIDS

5000+ ORGANOIDS

5000+ ORGANOIDS

4DCELL EXPERTISE CENTER

4Dcell discovery journey. From biology to decision.

Scientifique utilisant un microscope

​As a pioneer in microfabrication applied to biology, 4Dcell has developed a unique know-how to design easy-to-use, highly relevant human-based 3D cell models.
This expertise positions 4Dcell as a leader in the design of New Approach Methodologies (NAMs) and enables our design office to develop customized models tailored to your projects, accurately reproducing the in vitro organ systems you need.​​

Our approach is structured around 3 decision gates designed to build confidence and support informed decision-making:

CLARITY

CONFIDENCE

DECISION

Gate 0 – Project Scoping & Model Definition

4Dcell experts work closely with your scientific teams to clearly define the objectives, constraints, and success criteria of your project.

Selection of the right 4Dcell "Organoid maker" platform adapted to your needs:

Cardiac related projects
SmartHeart platform to support disease modeling and safety/toxicology assessments with human-relevant data.

Design Office: Contractile models
​​A dedicated platform for non-cardiac, contractile models (skeletal muscle, smooth muscle, uterine models, ...) powered by SmartContractility™ Technology.​

Design Office: Non-Contractile models
A general organoid-forming platform powered by SmartSphero™ Technology, enabling the generation of robust and reproducible organoids.

This project definition gate ensures that the selected models, functional readouts, and study design are fully adapted to your biological question, development stage, and decision-making needs.

Gate 1 – Model Engineering & Functional Characterization

For any cell source or disease model beyond our catalog:

  • Optimization of organoid assembly and maturation conditions

  • Assessment of viability and structural integrity

  • Evaluation of functional performance using appropriate readouts

  • Maximization of reproducibility and physiological relevance


Characterization at this stage ensures confidence in the model before it is used for screening, validation, or decision-making studies.

Gate 2 – Screening & Validation

We apply the validated models to screening and validation studies, generating high-quality functional data under acute or chronic conditions.

This final step supports compound selection, safety assessment, and translational decision-making, providing results that are robust, reproducible, and aligned with your development objectives.

DO YOU WANT TO PUSH THE LIMITS OF 3D CELL CULTURE? LET'S DISCUSS YOUR PROJECTS

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